Effective Preexposure Tuberculosis Vaccines Fail To Protect When They Are Given in an Immunotherapeutic Mode

Two vaccine formulations previously shown to induce protective immunity in mice and prevention of long-term necrosis in guinea pigs were tested as potential immunotherapeutic vaccines in mice earlier infected by aerosol with Mycobacterium tuberculosis. Neither vaccine had any effect on the course of...

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Bibliographic Details
Main Authors: Turner, Joanne, Rhoades, Elizabeth R., Keen, Marc, Belisle, John T., Frank, Anthony A., Orme, Ian M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97334/
https://ncbi.nlm.nih.gov/pubmed/10678993
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