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Bacterial Induction of Beta Interferon in Mice Is a Function of the Lipopolysaccharide Component

We investigated the reason for the inability of lipopolysaccharide (LPS)-resistant (Lps-defective [Lps(d)]) C57BL/10ScCr mice to produce beta interferon (IFN-β) when stimulated with bacteria. For this purpose, the IFN-β and other macrophage cytokine responses induced by LPS and several killed gram-n...

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Autori principali: Sing, Andreas, Merlin, Thomas, Knopf, Hans-Peter, Nielsen, Peter J., Loppnow, Harald, Galanos, Chris, Freudenberg, Marina A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC97320/
https://ncbi.nlm.nih.gov/pubmed/10678979
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