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Subunit Vaccination of Mice against New World Cutaneous Leishmaniasis: Comparison of Three Proteins Expressed in Amastigotes and Six Adjuvants

A mixture of well-defined recombinant antigens together with an adjuvant that preferentially stimulates specific gamma interferon (IFN-γ)-secreting helper type 1 CD4(+) T cells (Th1 cells) presents a rational option for a vaccine against leishmaniasis. The potential of this approach was investigated...

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Publicat a:Infect Immun
Autors principals: Aebischer, Toni, Wolfram, Markus, Patzer, Silke I., Ilg, Thomas, Wiese, Martin, Overath, Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97286/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10678945/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.3.1328-1336.2000
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