The Legionella pneumophila iraAB Locus Is Required for Iron Assimilation, Intracellular Infection, and Virulence

Legionella pneumophila, a facultative intracellular parasite of human alveolar macrophages and protozoa, causes Legionnaires' disease. Using mini-Tn10 mutagenesis, we previously isolated a L. pneumophila mutant that was hypersensitive to iron chelators. This mutant, NU216, and its allelic equivalent...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Viswanathan, V. K., Edelstein, Paul H., Pope, C. Dumais, Cianciotto, Nicholas P.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2000
Subjects:	Molecular and Cellular Pathogenesis
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97250/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10678909/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.3.1069-1079.2000
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