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Acquired Immunity to Chlamydia pneumoniae Is Dependent on Gamma Interferon in Two Mouse Strains That Initially Differ in This Respect after Primary Challenge

The role of gamma interferon (IFN-γ) in a Chlamydia pneumoniae mouse model was studied by in vivo neutralization in two inbred mouse strains. During primary C. pneumoniae infection, neutralization of IFN-γ increased both the numbers of bacteria and the pneumonia score in the lungs of C57BL/6 mice bu...

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Bibliografiske detaljer
Main Authors: Vuola, Jenni M., Puurula, Vuokko, Anttila, Marjukka, Mäkelä, P. Helena, Rautonen, Nina
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97231/
https://ncbi.nlm.nih.gov/pubmed/10639472
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