Effects of the Immunoglobulin A1 Protease on Neisseria gonorrhoeae Trafficking across Polarized T84 Epithelial Monolayers

We previously demonstrated that the Neisseria IgA1 protease cleaves LAMP1 (lysosome-associated membrane protein 1), a major integral membrane glycoprotein of lysosomes, thereby accelerating its degradation rate in infected A431 human epidermoid carcinoma cells and resulting in the alteration of lyso...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Hopper, Sylvia, Vasquez, Brandi, Merz, Alex, Clary, Susan, Wilbur, J. Scott, So, Magdalene
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2000
Subjects:	Molecular and Cellular Pathogenesis
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639461/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.2.906-911.2000
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