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The Cytotoxic T-Lymphocyte Epitope of the Plasmodium falciparum Circumsporozoite Protein Also Modulates the Efficiency of Receptor-Ligand Interaction with Hepatocytes

Malaria sporozoites are transmitted from the mosquito salivary gland to host hepatocytes within minutes of an infectious bite. The circumsporozoite protein (CS), which covers the surface of Plasmodium sporozoites, functions during these minutes in the targeting of host liver cells. The protein'...

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Bibliographic Details
Main Authors: Rathore, Dharmendar, McCutchan, Thomas F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97200/
https://ncbi.nlm.nih.gov/pubmed/10639441
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