Mannose-Binding Lectin Binds to a Range of Clinically Relevant Microorganisms and Promotes Complement Deposition

Mannose-binding lectin (MBL) is a collagenous serum lectin believed to be of importance in innate immunity. Genetically determined low levels of the protein are known to predispose to infections. In this study the binding of purified MBL to pathogens isolated from immunocompromised children was inve...

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Main Authors: Neth, Olaf, Jack, Dominic L., Dodds, Alister W., Holzel, Helen, Klein, Nigel J., Turner, Malcolm W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97193/
https://ncbi.nlm.nih.gov/pubmed/10639434
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