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Expression of the Helicobacter pylori ureI Gene Is Required for Acidic pH Activation of Cytoplasmic Urease

ureI encodes an integral cytoplasmic membrane protein. It is present in the urease gene cluster of Helicobacter pylori and is essential for infection and acid survival, but its role is unknown. To determine the function of UreI protein, we produced H. pylori ureI deletion mutants and measured the pH...

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Detalles Bibliográficos
Publicado en:Infect Immun
Principais autores: Scott, David R., Marcus, Elizabeth A., Weeks, David L., Lee, Adrian, Melchers, Klaus, Sachs, George
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2000
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97165/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639406/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.2.470-477.2000
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