Delivery of CD8(+) T-Cell Epitopes into Major Histocompatibility Complex Class I Antigen Presentation Pathway by Bordetella pertussis Adenylate Cyclase: Delineation of Cell Invasive Structures and Permissive Insertion Sites

Bordetella pertussis adenylate cyclase (AC) toxin-hemolysin (ACT-Hly) can penetrate a variety of eukaryotic cells. Recombinant AC toxoids have therefore been recently used for delivery of CD8(+) T-cell epitopes into antigen-presenting cells in vivo and for induction of protective antiviral, as well...

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Pubblicato in:	Infect Immun
Autori principali:	Osička, Radim, Osičková, Adriana, Basar, Tümay, Guermonprez, Pierre, Rojas, Marie, Leclerc, Claude, Šebo, Peter
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97128/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10603395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.1.247-256.2000
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