Murine Immune Response to Neisseria meningitidis Group C Capsular Polysaccharide: Analysis of Monoclonal Antibodies Generated in Response to a Thymus-Independent Antigen and a Thymus-Dependent Toxoid Conjugate Vaccine

Antibody (Ab) responses to polysaccharides (PSs) such as Neisseria meningitidis group C PS (MCPS) are characterized as being thymus independent (TI) and are restricted with regard to clonotype and isotype expression. PS conjugated to proteins, e.g., MCPS coupled to tetanus toxoid (MCPS-TT), elicits...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	García-Ojeda, Pablo A., Monser, Martha E., Rubinstein, Leonard J., Jennings, Harold J., Stein, Kathryn E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97127/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10603394/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.1.239-246.2000
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