Development of a ΔglnA Balanced Lethal Plasmid System for Expression of Heterologous Antigens by Attenuated Vaccine Vector Strains of Vibrio cholerae

We have previously shown that more prominent immune responses are induced to antigens expressed from multicopy plasmids in live attenuated vaccine vector strains of Vibrio cholerae than to antigens expressed from single-copy genes on the V. cholerae chromosome. Here, we report the construction of a...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Infect Immun
Prif Awduron:	Ryan, Edward T., Crean, Thomas I., Kochi, Sims K., John, Manohar, Luciano, Angel A., Killeen, Kevin P., Klose, Karl E., Calderwood, Stephen B.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 2000
Pynciau:	Microbial Immunity and Vaccines
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97124/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10603391/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.1.221-226.2000
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