Misexpression of the Opaque-Phase-Specific Gene PEP1 (SAP1) in the White Phase of Candida albicans Confers Increased Virulence in a Mouse Model of Cutaneous Infection

Candida albicans WO-1 switches reversibly and at high frequency between a white and an opaque colony-forming phenotype that includes dramatic changes in cell morphology and physiology. A misexpression strategy has been used to investigate the role of the opaque-phase-specific gene PEP1 (SAP1), which...

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Pubblicato in:	Infect Immun
Autori principali:	Kvaal, Christopher, Lachke, Salil A., Srikantha, Thyagarajan, Daniels, Karla, McCoy, James, Soll, David R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97079/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10569787/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.12.6652-6662.1999
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