Peptide Localization and Gene Structure of Cryptdin 4, a Differentially Expressed Mouse Paneth Cell α-Defensin

Paneth cells in crypts of the small intestine express antimicrobial peptides, including α-defensins, termed cryptdins in mice. Of the known Paneth cell α-defensins, the cryptdin 4 gene is unique, because it is inactive in the duodenum and expressed at maximal levels in the distal small bowel (D. Dar...

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Autors principals: Ouellette, Andre J., Darmoul, Dalila, Tran, Dat, Huttner, Kenneth M., Yuan, Jun, Selsted, Michael E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1999
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC97078/
https://ncbi.nlm.nih.gov/pubmed/10569786
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