Production of Tumor Necrosis Factor Alpha in Human T Lymphocytes by Staphylococcal Enterotoxin B Correlates with Toxin-Induced Proliferation and Is Regulated through Protein Kinase C

The superantigen staphylococcal enterotoxin B (SEB) simultaneously binds both the major histocompatibility complex (MHC) class II receptor on monocytes and the T-cell receptor (TCR) on T lymphocytes, resulting in a range of cell responses including induction of tumor necrosis factor alpha (TNF-α). I...

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Bibliographic Details
Main Authors: Yan, Zhengyin, Yang, David C. H., Neill, Roger, Jett, Marti
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1999
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97074/
https://ncbi.nlm.nih.gov/pubmed/10569782
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