Streptococcal Histone Induces Murine Macrophages To Produce Interleukin-1 and Tumor Necrosis Factor Alpha

The histone-like protein (HlpA) is highly conserved among streptococci. After lysis of streptococci in infected tissues, HlpA can enter the bloodstream and bind to proteoglycans in the glomerular capillaries of kidneys, where it can react with antibodies or stimulate host cell receptors. Deposits of...

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Main Authors: Zhang, Liping, Ignatowski, Tracey A., Spengler, Robert N., Noble, Bernice, Stinson, Murray W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1999
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC97057/
https://ncbi.nlm.nih.gov/pubmed/10569765
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