Targeting Improves the Efficacy of a DNA Vaccine against Corynebacterium pseudotuberculosis in Sheep

A large-scale DNA vaccination trial was performed with sheep to investigate whether an antigen targeted by CTLA-4 enhanced and accelerated the humoral immune response. Vaccination with genetically detoxified phospholipase D (ΔPLD) has been shown to be effective, at least partially, against Corynebac...

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Bibliographic Details
Main Authors: Chaplin, Paul J., De Rose, Robert, Boyle, Jefferey S., McWaters, Peter, Kelly, Julie, Tennent, Jan M., Lew, Andrew M., Scheerlinck, Jean-Pierre Y.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1999
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97052/
https://ncbi.nlm.nih.gov/pubmed/10569760
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