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Targeted Salivary Gland Immunization with Plasmid DNA Elicits Specific Salivary Immunoglobulin A and G Antibodies and Serum Immunoglobulin G Antibodies in Mice

For the development of vaccines against oral and pharyngeal pathogens invading the mucosal epithelia, both secretory and serum immunoglobulin A (IgA) and IgG antibodies and cytotoxic T lymphocytes (CTL) have been induced. We used a novel approach, targeted salivary gland (TSG) immunization, using pl...

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Main Authors: Kawabata, Shigetada, Terao, Yutaka, Fujiwara, Taku, Nakagawa, Ichiro, Hamada, Shigeyuki
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC96967/
https://ncbi.nlm.nih.gov/pubmed/10531241
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