Monoclonal Antibody to Shiga Toxin 2 Which Blocks Receptor Binding and Neutralizes Cytotoxicity

A monoclonal antibody (MAb) was raised against Shiga toxin 2 (Stx2) of Escherichia coli O157:H7. MAb VTm1.1 belonged to the immunoglobulin G1 subclass and had a κ light chain, and it could neutralize the cytotoxic activity of Stx2 and variants derived from patient strains but not that of variants de...

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Podrobná bibliografie

Vydáno v:	Infect Immun
Hlavní autoři:	Nakao, Hiroshi, Kiyokawa, Nobutaka, Fujimoto, Junichiro, Yamasaki, Shinji, Takeda, Tae
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Molecular and Cellular Pathogenesis
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10531220/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.11.5717-5722.1999
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