Phase Variation in Helicobacter pylori Lipopolysaccharide due to Changes in the Lengths of Poly(C) Tracts in α3-Fucosyltransferase Genes

The lipopolysaccharide (LPS) of Helicobacter pylori expresses the Lewis x (Le(x)) and/or Le(y) antigen. We have shown previously that H. pylori LPS displays phase variation whereby an Le(x)-positive strain yields variants with different LPS serotypes, for example, Le(x) plus Le(y) or nonfucosylated...

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Main Authors: Appelmelk, Ben J., Martin, Steve L., Monteiro, Mario A., Clayton, Chris A., McColm, Andrew A., Zheng, Pengyuan, Verboom, Theo, Maaskant, Janneke J., van den Eijnden, Dirk H., Hokke, Cornelis H., Perry, Malcolm B., Vandenbroucke-Grauls, Christina M. J. E., Kusters, Johannes G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Molecular and Cellular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96892/
https://ncbi.nlm.nih.gov/pubmed/10496917
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