Phase Variation in Helicobacter pylori Lipopolysaccharide due to Changes in the Lengths of Poly(C) Tracts in α3-Fucosyltransferase Genes

The lipopolysaccharide (LPS) of Helicobacter pylori expresses the Lewis x (Le(x)) and/or Le(y) antigen. We have shown previously that H. pylori LPS displays phase variation whereby an Le(x)-positive strain yields variants with different LPS serotypes, for example, Le(x) plus Le(y) or nonfucosylated...

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Autori principali: Appelmelk, Ben J., Martin, Steve L., Monteiro, Mario A., Clayton, Chris A., McColm, Andrew A., Zheng, Pengyuan, Verboom, Theo, Maaskant, Janneke J., van den Eijnden, Dirk H., Hokke, Cornelis H., Perry, Malcolm B., Vandenbroucke-Grauls, Christina M. J. E., Kusters, Johannes G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
Soggetti:
Molecular and Cellular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC96892/
https://ncbi.nlm.nih.gov/pubmed/10496917
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