A Two-Component Regulatory System, CsrR-CsrS, Represses Expression of Three Streptococcus pyogenes Virulence Factors, Hyaluronic Acid Capsule, Streptolysin S, and Pyrogenic Exotoxin B

Certain Tn916 insertions in the chromosome of an M1-type, nonmucoid Streptococcus pyogenes isolate (MGAS166) were previously shown to result in stable mucoidy with increased expression of the capsular synthetic genes. The transposon insertions in these strains are directly upstream of an apparent op...

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Bibliografiska uppgifter
Huvudupphovsmän: Heath, Andrew, DiRita, Victor J., Barg, Neil L., Engleberg, N. Cary
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1999
Ämnen:
Molecular and Cellular Pathogenesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC96884/
https://ncbi.nlm.nih.gov/pubmed/10496909
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