Dual Role of Interleukin-10 in Murine Lyme Disease: Regulation of Arthritis Severity and Host Defense

In the murine model of Lyme disease, C3H/He mice exhibit severe arthritis while C57BL/6N mice exhibit mild lesions when infected with Borrelia burgdorferi. Joint tissues from these two strains of mice harbor similar concentrations of B. burgdorferi, suggesting that the difference in disease severity...

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Main Authors: Brown, Jeanette P., Zachary, James F., Teuscher, Cory, Weis, Janis J., Wooten, R. Mark
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96863/
https://ncbi.nlm.nih.gov/pubmed/10496888
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