Differential Transcription of the tcpPH Operon Confers Biotype-Specific Control of the Vibrio cholerae ToxR Virulence Regulon

Epidemic strains of Vibrio cholerae O1 are divided into two biotypes, classical and El Tor. In both biotypes, regulation of virulence gene expression depends on a cascade in which ToxR activates expression of ToxT, and ToxT activates expression of cholera toxin and other virulence genes. In the clas...

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Autors principals: Murley, Yvette M., Carroll, Patricia A., Skorupski, Karen, Taylor, Ronald K., Calderwood, Stephen B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Molecular and Cellular Pathogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC96860/
https://ncbi.nlm.nih.gov/pubmed/10496885
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