Age-Associated Differences in Immunoglobulin G1 (IgG1) and IgG2 Subclass Antibodies to Pneumococcal Polysaccharides following Vaccination

Immunoglobulin G (IgG) subclass antibody responses to pneumococcal vaccines were determined for human subjects in four age groups. The ratios of IgG1/IgG2 antibody concentrations declined with advancing age for all five of the serotypes tested. Protein-conjugate vaccines elicited enhanced IgG antibo...

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Autors principals: Lottenbach, Kathleen R., Mink, ChrisAnna M., Barenkamp, Stephen J., Anderson, Edwin L., Homan, Sharon M., Powers, Douglas C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC96832/
https://ncbi.nlm.nih.gov/pubmed/10456954
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