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Genetic Control of Schistosome Infections by the SM1 Locus of the 5q31-q33 Region Is Linked to Differentiation of Type 2 Helper T Lymphocytes

Human susceptibility to Schistosoma mansoni infections is controlled by the SM1 locus on chromosome 5 in q31-q33. This genetic region encodes cytokines which regulate the development of helper T lymphocytes. In the present work, a clonal analysis of CD4(+) T lymphocytes of homozygous resistant and h...

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Detalhes bibliográficos
Main Authors: Rodrigues, Virmondes, Piper, Karen, Couissinier-Paris, Patricia, Bacelar, Olivia, Dessein, Hélia, Dessein, Alain J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96795/
https://ncbi.nlm.nih.gov/pubmed/10456917
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