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A Defect in Interleukin-10 Leads to Enhanced Malarial Disease in Plasmodium chabaudi chabaudi Infection in Mice

Infection of interleukin-10 (IL-10)-nonexpressing (IL-10(−/−)) mice with Plasmodium chabaudi chabaudi (AS) leads to exacerbated pathology in female mice and death in a proportion of them. Hypoglycemia, hypothermia, and loss in body weight were significantly greater in female IL-10(−/−) mice than in...

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Autori principali: Li, Ching, Corraliza, Inés, Langhorne, Jean
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC96762/
https://ncbi.nlm.nih.gov/pubmed/10456884
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