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Pathology of Plasmodium chabaudi chabaudi Infection and Mortality in Interleukin-10-Deficient Mice Are Ameliorated by Anti-Tumor Necrosis Factor Alpha and Exacerbated by Anti-Transforming Growth Factor β Antibodies

Interleukin-10 (IL-10)-deficient (IL-10(−/−)) mice infected with Plasmodium chabaudi (AS) suffer a more severe disease and exhibit a higher rate of mortality than control C57BL/6 mice. Here, we show that a drop in body temperature to below 28°C and pronounced hypoglycemia of below 3 mM are reliable...

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Sonraí Bibleagrafaíochta
Main Authors: Li, Ching, Sanni, Latifu A., Omer, Fakhreldin, Riley, Eleanor, Langhorne, Jean
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC187303/
https://ncbi.nlm.nih.gov/pubmed/12933825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.9.4850-4856.2003
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