Infectivity of Plasmodium berghei Sporozoites Delivered by Intravenous Inoculation versus Mosquito Bite: Implications for Sporozoite Vaccine Trials

Plasmodium berghei sporozoites delivered by mosquito bite were more infectious to outbred CD-1 mice than were sporozoites delivered by intravenous inoculation. The route of challenge also affected vaccine efficacy. In view of these findings and the fact that mosquito bites are the natural mode of sp...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Vaughan, Jefferson A., Scheller, Libia F., Wirtz, Robert A., Azad, Abdu F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Fungal and Parasitic Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10417207/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.8.4285-4289.1999
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