Infectivity of Plasmodium berghei Sporozoites Delivered by Intravenous Inoculation versus Mosquito Bite: Implications for Sporozoite Vaccine Trials

Plasmodium berghei sporozoites delivered by mosquito bite were more infectious to outbred CD-1 mice than were sporozoites delivered by intravenous inoculation. The route of challenge also affected vaccine efficacy. In view of these findings and the fact that mosquito bites are the natural mode of sp...

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Bibliografische gegevens
Hoofdauteurs: Vaughan, Jefferson A., Scheller, Libia F., Wirtz, Robert A., Azad, Abdu F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1999
Onderwerpen:
Fungal and Parasitic Infections
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96740/
https://ncbi.nlm.nih.gov/pubmed/10417207
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