Production of β-Defensin Antimicrobial Peptides by the Oral Mucosa and Salivary Glands

β-Defensins are cationic peptides with broad-spectrum antimicrobial activity that are produced by epithelia at mucosal surfaces. Two human β-defensins, HBD-1 and HBD-2, were discovered in 1995 and 1997, respectively. However, little is known about the expression of HBD-1 or HBD-2 in tissues of the o...

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Main Authors: Mathews, Michael, Jia, Hong Peng, Guthmiller, Janet M., Losh, Garrett, Graham, Scott, Johnson, Georgia K., Tack, Brian F., McCray, Paul B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC96577/
https://ncbi.nlm.nih.gov/pubmed/10338476
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