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Adaptive Immune Response to Shigella flexneri 2a cydC in Immunocompetent Mice and Mice Lacking Immunoglobulin A

Shigella flexneri cydC, which is deficient in cytochrome bd, was rapidly cleared from the lungs of intranasally inoculated mice and was Sereny negative, yet it induced 93% protection against challenge with wild-type S. flexneri. Mice that lack immunoglobulin A (IgA) were fully protected, suggesting...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Way, Sing Sing, Borczuk, Alain C., Goldberg, Marcia B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96558/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10085048/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.4.2001-2004.1999
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