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Vaccination and Protection of Pigs against Pleuropneumonia with a Vaccine Strain of Actinobacillus pleuropneumoniae Produced by Site-Specific Mutagenesis of the ApxII Operon
The production of toxin (Apx)-neutralizing antibodies during infection plays a major role in the induction of protective immunity to Actinobacillus pleuropneumoniae reinfection. In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromos...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
1999
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC96553/ https://ncbi.nlm.nih.gov/pubmed/10085043 |
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