Protective Efficacy of Recombinant Yersinia Outer Proteins against Bubonic Plague Caused by Encapsulated and Nonencapsulated Yersinia pestis

To evaluate the role of Yersinia outer proteins (Yops) in conferring protective immunity against plague, six yop loci from Yersinia pestis were individually amplified by PCR, cloned, and expressed in Escherichia coli. The recombinant proteins were purified and injected into mice. Most Yop-vaccinated...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Andrews, G. P., Strachan, S. T., Benner, G. E., Sample, A. K., Anderson, G. W., Adamovicz, J. J., Welkos, S. L., Pullen, J. K., Friedlander, A. M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10024607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.3.1533-1537.1999
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