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Neutralization of Endotoxin In Vitro and In Vivo by a Human Lactoferrin-Derived Peptide

Endotoxin (lipopolysaccharide [LPS]) is the major pathogenic factor of gram-negative septic shock, and endotoxin-induced death is associated with the host overproduction of tumor necrosis factor alpha (TNF-α). In the search for new antiendotoxin molecules, we studied the endotoxin-neutralizing capac...

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Autori principali: Zhang, Gui-Hang, Mann, David M., Tsai, Chao-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC96468/
https://ncbi.nlm.nih.gov/pubmed/10024582
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