Gamma Interferon Stimulates Rat Alveolar Macrophages To Kill Pneumocystis carinii by l-Arginine- and Tumor Necrosis Factor-Dependent Mechanisms

Pneumocystis carinii pneumonia remains a serious complication for immunocompromised patients. In the present study, P. carinii organisms interacted with gamma interferon (IFN-γ)-stimulated alveolar macrophages (AMs) to activate the l-arginine-dependent cytocidal pathway involving reactive nitrogen i...

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Bibliographic Details
Main Authors: Downing, James F., Kachel, Diane L., Pasula, Rajamouli, Martin, William J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC96467/
https://ncbi.nlm.nih.gov/pubmed/10024581
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