Hyperproduction of Alpha-Hemolysin in a sigB Mutant Is Associated with Elevated SarA Expression in Staphylococcus aureus

To evaluate the role of SigB in modulating the expression of virulence determinants in Staphylococcus aureus, we constructed a sigB mutant of RN6390, a prototypic S. aureus strain. The mutation in the sigB gene was confirmed by the absence of the SigB protein in the mutant on an immunoblot as well a...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Cheung, Ambrose L., Chien, Yueh-tyng, Bayer, Arnold S.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Molecular and Cellular Pathogenesis
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96465/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10024579/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.3.1331-1337.1999
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