Pathogenicity Island 2 Mutants of Salmonella typhimurium Are Efficient Carriers for Heterologous Antigens and Enable Modulation of Immune Responses

The potential use as vaccine delivery system of Salmonella typhimurium strains harboring defined mutations in the sseC (HH104) and sseD (MvP101) genes, which encode putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2, was evaluated and compared with that...

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Autors principals: Medina, Eva, Paglia, Paola, Nikolaus, Thomas, Müller, Astrid, Hensel, Michael, Guzmán, Carlos A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC96434/
https://ncbi.nlm.nih.gov/pubmed/10024548
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