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Cytotoxic Action of Serratia marcescens Hemolysin on Human Epithelial Cells

Incubation of human epithelial cells with nanomolar concentrations of chromatographically purified Serratia marcescens hemolysin (ShlA) caused irreversible vacuolation and subsequent lysis of the cells. Vacuolation differed from vacuole formation by Helicobacter pylori VacA. Sublytic doses of ShlA l...

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Bibliographische Detailangaben
Hauptverfasser: Hertle, Ralf, Hilger, Martina, Weingardt-Kocher, Sandra, Walev, Iwan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96392/
https://ncbi.nlm.nih.gov/pubmed/9916096
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