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Glucose 6-Phosphate Dehydrogenase Is Required for Salmonella typhimurium Virulence and Resistance to Reactive Oxygen and Nitrogen Intermediates

Salmonella typhimurium zwf mutants lacking glucose 6-phosphate dehydrogenase (G6PD) activity have increased susceptibility to reactive oxygen and nitrogen intermediates as well as attenuated virulence in mice. Abrogation of the phagocyte respiratory burst oxidase during experimental infection with z...

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Bibliographic Details
Main Authors: Lundberg, Brita E., Wolf, Richard E., Dinauer, Mary C., Xu, Yisheng, Fang, Ferric C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC96332/
https://ncbi.nlm.nih.gov/pubmed/9864251
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