Antisense Inhibition of Expression of Cysteine Proteinases Affects Entamoeba histolytica-Induced Formation of Liver Abscess in Hamsters

Trophozoites of virulent Entamoeba histolytica transfected with the antisense gene encoding cysteine proteinase 5 (CP5) have only 10% of the CP activity but retain their cytopathic activity on mammalian monolayers. In the present study we found that the transfected trophozoites with low levels of CP...

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Autores principales: Ankri, Serge, Stolarsky, Tamara, Bracha, Rivka, Padilla-Vaca, Felipe, Mirelman, David
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Molecular and Cellular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC96327/
https://ncbi.nlm.nih.gov/pubmed/9864246
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