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Five Homologous Repeats of the Protein G-Related Protein MIG Cooperate in Binding to Goat Immunoglobulin G

Protein MIG, from Streptococcus dysgalactiae, binds α(2)-macroglobulin and immunoglobulin G (IgG). MIG-derived fusion proteins with one to five IgG-binding repeats differed up to 72,000-fold in avidity for goat IgG, indicating a considerable cooperativity of the repeats. Significant sequence variati...

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Detalles Bibliográficos
Main Authors: Vasi, József, Svensson, Jan, Frick, Inga-Maria, Müller, Hans-Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC96325/
https://ncbi.nlm.nih.gov/pubmed/9864244
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