Inhibition of Ganciclovir-Susceptible and -Resistant Human Cytomegalovirus Clinical Isolates by the Benzimidazole l-Riboside 1263W94

The average 50% inhibitory concentration (IC(50)) values for AD169 were 0.22 ± 0.09 μM 1263W94 and 5.36 ± 0.12 μM ganciclovir. For 35 human cytomegalovirus (HCMV) clinical isolates the average IC(50) was 0.42 ± 0.09 μM 1263W94, and for 26 ganciclovir-susceptible HCMV clinical isolates the average IC...

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Main Authors: McSharry, James J., McDonough, Ann, Olson, Betty, Talarico, Christine, Davis, Michele, Biron, Karen K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Microbial Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC96263/
https://ncbi.nlm.nih.gov/pubmed/11687477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.8.6.1279-1281.2001
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