Abnormal CD40 Ligand (CD154) Expression in Human Immunodeficiency Virus-Infected Children

The CD40 ligand (CD154), expressed primarily on activated CD4-positive T cells, is a costimulatory molecule involved in B-cell proliferation, germinal center formation, and immunoglobulin class switching. Since B-cell abnormalities including hypergammaglobulinemia and abnormal antibody-specific immu...

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Main Authors: O'Gorman, Maurice R. G., DuChateau, Brian, Paniagua, Mary, Hunt, Janelle, Bensen, Nicolas, Yogev, Ram
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Cellular Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC96233/
https://ncbi.nlm.nih.gov/pubmed/11687447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.8.6.1104-1109.2001
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