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T-Cell Receptor Vβ Repertoire CDR3 Length Diversity Differs within CD45RA and CD45RO T-Cell Subsets in Healthy and Human Immunodeficiency Virus-Infected Children

The T-cell receptor (TCR) CDR3 length heterogeneity is formed during recombination of individual Vβ gene families. We hypothesized that CDR3 length diversity could be used to assess the fundamental differences within the TCR repertoire of CD45RA and CD45RO T-cell subpopulations. By using PCR-based s...

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Pubblicato in:Clin Diagn Lab Immunol
Autori principali: Kou, Zhong Chen, Puhr, Joshua S., Rojas, Mabel, McCormack, Wayne T., Goodenow, Maureen M., Sleasman, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95992/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11063505/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/cdli.7.6.953-959.2000
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