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Identification of a Subset of Common Variable Immunodeficiency Patients with Impaired B-Cell Protein Tyrosine Phosphorylation

The mechanisms responsible for common variable immunodeficiency syndrome (CVID) are as yet unknown. In the present study, we show that the B-cell dysfunction in a subset of CVID patients is caused by defective protein tyrosine phosphorylation (PTP). We demonstrated that the PTP level and immunoglobu...

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Detalhes bibliográficos
Main Authors: Schwartz, Rivka, Porat, Yael Ben-Anat, Handzel, Zeev, Sthoeger, Zeev, Garty, Ben-Zion, Confino-Cohen, Ronit, Levy, Jacov, Zan-Bar, Israel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC95788/
https://ncbi.nlm.nih.gov/pubmed/10548576
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