Conversion of Pipecolic Acid into Lysine in Penicillium chrysogenum Requires Pipecolate Oxidase and Saccharopine Reductase: Characterization of the lys7 Gene Encoding Saccharopine Reductase

Pipecolic acid is a component of several secondary metabolites in plants and fungi. This compound is useful as a precursor of nonribosomal peptides with novel pharmacological activities. In Penicillium chrysogenum pipecolic acid is converted into lysine and complements the lysine requirement of thre...

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Bibliographic Details
Main Authors: Naranjo, Leopoldo, de Valmaseda, Eva Martin, Bañuelos, Oscar, Lopez, Pilar, Riaño, Jorge, Casqueiro, Javier, Martin, Juan F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Physiology and Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC95565/
https://ncbi.nlm.nih.gov/pubmed/11717275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.24.7165-7172.2001
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