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Residue Aspartate-147 from the Third Transmembrane Region of Na(+)/H(+) Antiporter NhaB of Vibrio alginolyticus Plays a Role in Its Activity

NhaB is a bacterial Na(+)/H(+) antiporter with unique topology. The pH dependence of NhaB from Vibrio alginolyticus differs from that of the Escherichia coli NhaB homolog. Replacement of Asp-147 with Glu made high H(+) concentrations a requirement for the NhaB activity. Replacement of Asp-147 with n...

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Detalhes bibliográficos
Main Authors: Nakamura, Tatsunosuke, Fujisaki, Yumiko, Enomoto, Hiromi, Nakayama, Yuji, Takabe, Teruhiro, Yamaguchi, Naoto, Uozumi, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC95471/
https://ncbi.nlm.nih.gov/pubmed/11544242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.19.5762-5767.2001
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