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Functional Analysis of OleY l-Oleandrosyl 3-O-Methyltransferase of the Oleandomycin Biosynthetic Pathway in Streptomyces antibioticus

Oleandomycin, a macrolide antibiotic produced by Streptomyces antibioticus, contains two sugars attached to the aglycon: l-oleandrose and d-desosamine. oleY codes for a methyltransferase involved in the biosynthesis of l-oleandrose. This gene was overexpressed in Escherichia coli to form inclusion b...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Rodríguez, Leticia, Rodríguez, David, Olano, Carlos, Braña, Alfredo F., Méndez, Carmen, Salas, José A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95419/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11514520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.18.5358-5363.2001
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