Functional Analysis of OleY l-Oleandrosyl 3-O-Methyltransferase of the Oleandomycin Biosynthetic Pathway in Streptomyces antibioticus

Oleandomycin, a macrolide antibiotic produced by Streptomyces antibioticus, contains two sugars attached to the aglycon: l-oleandrose and d-desosamine. oleY codes for a methyltransferase involved in the biosynthesis of l-oleandrose. This gene was overexpressed in Escherichia coli to form inclusion b...

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Bibliographische Detailangaben
Hauptverfasser: Rodríguez, Leticia, Rodríguez, David, Olano, Carlos, Braña, Alfredo F., Méndez, Carmen, Salas, José A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Enzymes and Proteins
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC95419/
https://ncbi.nlm.nih.gov/pubmed/11514520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.18.5358-5363.2001
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