The Histone Deacetylase Genes HDA1 and RPD3 Play Distinct Roles in Regulation of High-Frequency Phenotypic Switching in Candida albicans

Five histone deacetylase genes (HDA1, RPD3, HOS1, HOS2, and HOS3) have been cloned from Candida albicans and characterized. Sequence analysis and comparison with 17 additional deacetylases resulted in a phylogenetic tree composed of three major groups. Transcription of the deacetylases HDA1 and RPD3...

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Main Authors: Srikantha, T., Tsai, L., Daniels, K., Klar, A. J. S., Soll, D. R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Eukaryotic Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC95357/
https://ncbi.nlm.nih.gov/pubmed/11443097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.15.4614-4625.2001
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