Characterization of Escherichia coli Type 1 Pilus Mutants with Altered Binding Specificities

PCR mutagenesis and a unique enrichment scheme were used to obtain two mutants, each with a single lesion in fimH, the chromosomal gene that encodes the adhesin protein (FimH) of Escherichia coli type 1 pili. These mutants were noteworthy in part because both were altered in the normal range of cell...

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Bibliographic Details
Main Authors: Harris, Sandra L., Spears, Patricia A., Havell, Edward A., Hamrick, Terri S., Horton, John R., Orndorff, Paul E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Cell Surfaces
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC95295/
https://ncbi.nlm.nih.gov/pubmed/11395476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.13.4099-4102.2001
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