SsrA-Mediated Tagging in Bacillus subtilis

A general mechanism in bacteria to rescue stalled ribosomes involves a stable RNA encoded by the ssrA gene. This RNA, termed tmRNA, encodes a proteolytic peptide tag which is cotranslationally added to truncated polypeptides, thereby targeting them for rapid proteolysis. To study this ssrA-mediated...

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Bibliographic Details
Main Authors: Wiegert, Thomas, Schumann, Wolfgang
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC95270/
https://ncbi.nlm.nih.gov/pubmed/11395451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.13.3885-3889.2001
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